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This photo released May 1, 2013 by the U.S. Attorney's office in a federal criminal complaint, shows fireworks, which the complaint said federal agents recovered from inside a backpack belonging to Boston Marathon bombing suspect Dzhokhar Tsarnaeva, found in a landfill in New Bedford, Mass. Three men who attended the University of Massachusetts at Dartmouth with Tsarnaeva, were charged Wednesday, May 1, 2013, in connection with the case. (AP Photo/U.S. Attorney's Office)
This photo released May 1, 2013 by the U.S. Attorney's office in a federal criminal complaint, shows fireworks, which the complaint said federal agents recovered from inside a backpack belonging to Boston Marathon bombing suspect Dzhokhar Tsarnaeva, found in a landfill in New Bedford, Mass. Three men who attended the University of Massachusetts at Dartmouth with Tsarnaeva, were charged Wednesday, May 1, 2013, in connection with the case. (AP Photo/U.S. Attorney's Office)
A Department of Homeland Security police officer patrols with his dog outside the Moakley Federal Courthouse in Boston, Mass., Wednesday, May 1, 2013. Three suspects were taken into custody in the Boston Marathon bombing case including two college friends of Dzhokhar Tsarneav, according to officials. (AP Photo/Charles Krupa)
FILE - In this April 15, 2013 file photo, medical workers aid injured people at the finish line of the 2013 Boston Marathon following a bomb explosion in Boston, Monday, April 15, 2013. In addition to Tamerlan Tsarnaev, who died after a gunfight with police, and his brother, Dzhokhar Tsarnaev, who was captured and lies in a hospital prison, three more suspects in the bombings were taken into custody, Boston police said Wednesday, May 1, 2013. (AP Photo/Charles Krupa, File)
FILE - This combination of undated file photos shows Tamerlan Tsarnaev, 26, left, and Dzhokhar Tsarnaev, 19. The FBI says the two brothers are the suspects in the Boston Marathon bombing, and are also responsible for killing an MIT police officer, critically injuring a transit officer in a firefight and throwing explosive devices at police during a getaway attempt in a long night of violence that left Tamerlan dead and Dzhokhar captured, late Friday, April 19, 2013. The ethnic Chechen brothers lived in Dagestan, which borders the Chechnya region in southern Russia. They lived near Boston and had been in the U.S. for about a decade, one of their uncles reported said. Since Monday, Boston has experienced five days of fear, beginning with the marathon bombing attack, an intense manhunt and much uncertainty ending in the death of one suspect and the capture of the other. (AP Photo/The Lowell Sun & Robin Young, File)
BOSTON (AP) ? Three college friends of Boston Marathon bombing suspect Dzhokhar Tsarnaev were arrested and accused Wednesday of removing a backpack containing hollowed-out fireworks from Tsarnaev's dorm room three days after the attack to keep him from getting into trouble.
In court papers, the FBI said one of them threw the backpack in the garbage ? it was later found in a landfill by law enforcement officers ? after the young men concluded from news reports that Tsarnaev was one of the bombers.
Azamat Tazhayakov and Dias Kadyrbayev, both 19-year-olds from Kazakhstan, were charged with conspiring to obstruct justice by concealing and destroying evidence. Robel Phillipos, 19, who graduated from the prestigious Cambridge Rindge and Latin High School with Tsarnaev, was charged with lying to investigators about the visit to Tsarnaev's room.
The three were not accused of any involvement in the bombing itself. But in a footnote in the court papers outlining the charges, the FBI said that about a month before the bombing, Tsarnaev told Tazhayakov and Kadyrbayev that he knew how to make a bomb.
The lawyers for the Kazakh students said their clients had nothing to do with the bombing and were just as shocked by the crime as everyone else. Phillipos' attorney, Derege Demissie, said outside court: "The only allegation is he made a misrepresentation."
At a court appearance in the afternoon, the Kazakh students did not request bail and will be held for another hearing May 14. Phillipos was held for a hearing on Monday.
Three people were killed and more than 260 injured on April 15 when two bombs exploded near the finish line. Tamerlan Tsarnaev died after a gunfight with police days later. His younger brother, Dzhokhar Tsarnaev, a 19-year-old sophomore at the University of Massachusetts at Dartmouth, was captured and lies in a prison hospital.
Investigators have not said whether the pressure cooker bombs used in the attacks were made with gunpowder extracted from fireworks.
Tazhayakov and Kadyrbayev have been held in jail for more than a week on allegations they violated their student visas by not regularly going to class at UMass. All three men charged Wednesday began attending UMass with Tsarnaev in 2011, according to the FBI.
If convicted, Kadyrbayev and Tazhayakov could get up to five years in prison and a $250,000 fine. Phillipos faces a maximum of eight years behind bars and a $250,000 fine.
Authorities allege that on the night of April 18, after the FBI released surveillance-camera photos of the bombing suspects and the three men suspected their friend was one of them, they went to Tsarnaev's dorm room.
Before Tsarnaev's roommate let them in, Kadyrbayev showed Tazhayakov a text message from Tsarnaev that read: "I'm about to leave if you need something in my room take it," according to the FBI. When Tazhayakov learned of the message, "he believed he would never see Tsarnaev alive again," the FBI said in the affidavit.
It was not clear from the court papers whether authorities believe that was an instruction from Tsarnaev to his friends to destroy evidence.
Once inside Tsarnaev's room, the men noticed a backpack containing fireworks, which had been opened and emptied of powder, the FBI said.
The FBI said that Kadyrbayev knew when he saw the empty fireworks that Tsarnaev was involved in the bombings and decided to remove the backpack from the room "in order to help his friend Tsarnaev avoid trouble."
Kadyrbayev also decided to remove Tsarnaev's laptop "because he did not want Tsarnaev's roommate to think he was stealing or behaving suspiciously by just taking the backpack," the FBI said in court papers.
After the three men returned to Kadyrbayev's and Tazhayakov's apartment with the backpack and computer, they watched news reports featuring photographs of Tsarnaev.
The FBI affidavit said Kadyrbayev told authorities the three men then "collectively decided to throw the backpack and fireworks into the trash because they did not want Tsarnaev to get into trouble."
Kadyrbayev said he placed the backpack and fireworks along with trash from the apartment into a large trash bag and threw it into a garbage bin near the men's apartment.
When the backpack was later found in a landfill last week, inside it was a UMass-Dartmouth homework assignment sheet from a class Tsarnaev was taking, the FBI said.
Kadyrbayev and Tazhayakov lived at an off-campus apartment in New Bedford, about 60 miles south of Boston, and got around in a car registered to Kadyrbayev with a souvenir plate that read "Terrorista (hash)1." The car was pictured on Tsarnaev's Twitter feed in March.
The plate was a gag gift from some of Kadyrbayev's friends, meant to invoke his penchant for late-night partying rather than his political sentiments, a lawyer for Kadyrbayev said last week.
Michael McKeown, 20, went to high school with Dzhokjar and Phillipos and served with Phillipos on the Cambridge Kids' Council.
"He wasn't a stupid kid," the Boston University sophomore said of Phillipos. "I'm surprised he would do something this foolish."
___
Contributing to this report were Associated Press writers Allen G. Breed in Raleigh, N.C., Michelle R. Smith in Providence, R.I.; and Rodrique Ngowi in Boston.
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FILE - In this Wednesday, Nov. 30, 2011 file photo, former Israeli Foreign Minister Tzipi Livni attends a news conference at the Knesset, Israel's parliament, in Jerusalem. The Arab League?s decision to sweeten its decade-old proposal offering comprehensive peace with Israel has placed Prime Minister Benjamin Netanyahu in a bind and swiftly exposed fissures in his new government. "This is a positive announcement," negotiator Tzipi Livni told Channel 10 TV, adding it gave ?tail wind? to peace efforts. "At the end you need a direct negotiation between the Israelis and the Palestinians." (AP Photo/Sebastian Scheiner, File)
FILE - In this Wednesday, Nov. 30, 2011 file photo, former Israeli Foreign Minister Tzipi Livni attends a news conference at the Knesset, Israel's parliament, in Jerusalem. The Arab League?s decision to sweeten its decade-old proposal offering comprehensive peace with Israel has placed Prime Minister Benjamin Netanyahu in a bind and swiftly exposed fissures in his new government. "This is a positive announcement," negotiator Tzipi Livni told Channel 10 TV, adding it gave ?tail wind? to peace efforts. "At the end you need a direct negotiation between the Israelis and the Palestinians." (AP Photo/Sebastian Scheiner, File)
JERUSALEM (AP) ? The Arab League's decision to sweeten its decade-old proposal offering comprehensive peace with Israel has placed Prime Minister Benjamin Netanyahu in a bind and swiftly exposed fissures in his new government.
Netanyahu's chief peace negotiator on Tuesday welcomed the modified Arab proposal, while the prime minister remained silent, reflecting the internal divisions that lie ahead as the U.S. tries to restart long-frozen peace talks with the Palestinians.
"This is a positive announcement," negotiator Tzipi Livni told Channel 10 TV, adding it gave "tail wind" to peace efforts. "At the end you need a direct negotiation between the Israelis and the Palestinians."
The original 2002 Arab peace initiative offered Israel peace with the entire Arab and Muslim world in exchange for a "complete withdrawal" from territories captured in the 1967 Mideast war. The Palestinians claim the West Bank, east Jerusalem and the Gaza Strip, all seized by Israel in 1967, for their future state.
The initiative was revolutionary when it was introduced by Saudi Arabia's then crown prince, King Abdullah, and endorsed by the 22-member Arab League. The 57-member Organization of Islamic Cooperation later endorsed the plan as well. However, it was overshadowed by fierce Israeli-Palestinian fighting at the time and greeted with skepticism by Israel.
In Washington Monday, Qatari Prime Minister Sheik Hamad Bin Jassem Al Thani tried to allay some of the Israeli concerns. Speaking on behalf of an Arab League delegation, he reiterated the need to base an agreement between Israel and a future Palestine on the 1967 lines, but for the first time, he cited the possibility of "comparable," mutually agreed and "minor" land swaps between the Israelis and the Palestinians.
Sheik Hamad spoke after talks with Vice President Joe Biden and U.S. Secretary of State John Kerry, who has been pushing Arab leaders to embrace a modified version of the Arab peace plan as part of a new U.S.-led effort to corral Israel and the Palestinians back into direct peace talks. The changes are meant to win Israeli support by allowing it to keep parts of the West Bank and east Jerusalem as part of an agreement.
In Washington, Kerry called the changed language a "very big step forward."
"This is literally a statement by the Arab world that they're prepared to make peace, providing the Palestinians and Israelis reach a final status agreement," he told reporters Tuesday at the State Department after meeting Spain's foreign minister.
"I don't underestimate the significance of Saudi Arabia, Qatar, Arab Emirates, the Egyptians, the Jordanians and others coming to the table and saying, 'We are prepared to make peace now in 2013,'" he said. Still, he said much more was left to do.
"We have a lot of homework to do, a lot of tough hurdles to get over, but each step forward is the way you get there," Kerry said.
The gesture immediately put Netanyahu in a difficult position. A cool reception to the Arab League could reinforce the international perception that Netanyahu is not serious about pursuing peace. President Barack Obama has already endorsed the 1967 lines as the basis for talks, and past negotiations between Israel and the Palestinians have endorsed the concept of small land swaps.
But forces in Israel could doom the plan before it ever gets off the ground. Netanyahu himself has repeatedly said the 1967 frontiers would put Israel's security in danger and said he is not bound by any concessions made by his predecessors. In addition, the hard-liners who dominate his coalition would resist the concessions required by the Arab plan.
Netanyahu's office declined requests for comment Tuesday. But Cabinet minister Silvan Shalom, a senior member of Netanyahu's Likud Party, played down the Arab League's decision, saying, "there is nothing new here."
"In principle, I support renewing the process. Of course, I don't accept the 1967 lines," he told Israel Radio. "If the Arab League wants to be a partner to this process, then we welcome it, but this is not negotiations."
At the same time, the more dovish members of his coalition are likely to press Netanyahu to embrace the latest Arab approach.
Livni, while acknowledging that Israel had concerns about some of the details of the Arab initiative, said Israel must nonetheless respond positively. "It's good news that should be welcomed," she said in a Facebook post.
She noted that the plan gave the Palestinians important backing from the broader Arab world to make small concessions on the border issue, while it sent an important message to Israel that peace with the Palestinians means peace with the entire Arab world. "I hope that the message that comes from Qatar will help launch the negotiations as soon as possible."
Livni also served as chief negotiator during the last serious round of talks, in 2008, under then-Prime Minister Ehud Olmert. Both sides have said they made great progress toward a final border deal based on the 1967 lines.
Yesh Atid, a centrist coalition partner, could also put pressure on Netanyahu to embrace the Arab plan. Party leader Yair Lapid has said he would demand the government conduct a "serious" peace process with the Palestinians. He has also endorsed the concept of land swaps so that Israel can keep certain Jewish settlements in the West Bank.
Dov Lipman, a Yesh Atid lawmaker, said the party had not yet formulated a formal response to the Arab initiative, but said it was "very consistent" with the party's platform. "We need to be negotiating. It's the only way to solve the conflict," he said.
And President Shimon Peres, a Nobel peace laureate, said the Arabs' decision provided a new chance to restart peace talks. "The ministers of the Arab League once again expressed their support for the two state solution, which is also accepted by us and a broad structure of support is being created for making progress," he said during a meeting with Pope Francis at the Vatican.
Members of the opposition Labor Party urged Netanyahu to accept the Arab initiative.
"I think the Israeli government should embrace it with both hands," said Erel Margalit, a Labor lawmaker. "This is the breakthrough we have been looking for."
Margalit said he was in the process of forming a parliamentary lobby to support the initiative, and said Labor would support Netanyahu from the opposition if he embraced the plan.
Negotiations have been frozen since late 2008, in large part because of continued Israeli settlement construction in the West Bank and east Jerusalem.
Agreeing on the contours of future borders could resolve the settlement dispute at the outset of talks. The Arab initiative in effect endorses the Palestinian position on borders, while offering Israel the vision of a broader regional peace.
While the Palestinians voiced objections to modifying the Arab League plan, their chief negotiator, Saeb Erekat, said Tuesday that the Palestinians supported the new proposal.
"Israeli rejection of this initiative shows once again that the Israeli government lacks of a peace plan," he said in a statement. "Rather, it is fully engaged in further colonization and attacks against Palestinian rights and regional stability."
___
Associated Press writers Bradley Klapper in Washington and Mohammed Daraghmeh in Ramallah, West Bank, contributed to this report.
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Geneticist Emily Bates of Brigham Young University was on a team studying the link between sleep patterns and migraine.
Mark A. Philbrick/Courtesy of Brigham Young UniversityGeneticist Emily Bates of Brigham Young University was on a team studying the link between sleep patterns and migraine.
Mark A. Philbrick/Courtesy of Brigham Young UniversityBates experienced migraines as a child. She made this painting to depict how they felt to her.
Courtesy of Emily BatesBates experienced migraines as a child. She made this painting to depict how they felt to her.
Courtesy of Emily BatesMutations on a single gene appear to increase the risk for both an unusual sleep disorder and migraines, a team reports in Science Translational Medicine.
The finding could help explain the links between sleep problems and migraines. It also should make it easier to find new drugs to treat migraines, researchers say.
And for one member of the research team, Emily Bates, the discovery represents a personal victory.
Bates remembers getting a lot of migraines in elementary school. They would start with nausea and changes in vision, she says. Then came the pain.
"Loud sounds and light kind of hurt my eyes and my ears and my head," she says. Moving or applying any sort of pressure to her skin also hurt.
The problem was embarrassing and caused her to miss a lot of school, Bates says. It also was frustrating, she says, because back then, in the 1990s, no one could tell her much about what was causing her migraines or how to stop them.
So Bates decided to become a scientist in order to understand "these bizarre, awful migraines." She earned a doctorate in genetics at Harvard in 2005. Then, a couple of years later, while working in a lab at the University of California, San Francisco, she got a remarkable opportunity.
Researchers in Los Angeles had been studying a family with a lot of migraines. The team discovered something really surprising about this family: They were early birds who were usually asleep by 8 p.m. and up by 5 a.m. The scientific name for the condition is "advanced sleep phase."
The researchers were able to trace the family's sleep disorder to a mutation on a gene that helps control circadian rhythms, says Andrew Charles, a neurologist at UCLA. "We then turned our attention to the question of how this gene mutation could be involved in migraine," he says.
The first step was to show that the gene really could cause both sleep problems and migraines. So the team found a second family being studied at UCSF that had a slightly different mutation on the same gene. Sure enough, many members of this family were also early birds who had migraines.
The next step was to study mice carrying the mutated gene. And that's where Emily Bates got a chance to help explain the disorder that had so disrupted her childhood.
Bates' boss at UCSF, Louis Ptacek, had asked her to study the behavior of mice carrying the mutated gene and to find out whether they were experiencing any symptoms of migraines.
There's no sure way to know if a mouse has a headache, Bates says. So she began looking for some of the other migraine symptoms she knew so well ? things like sensitivity to heat and touch ? and she found them.
"All of the things that we looked at basically said these mice are more susceptible to migraine than a normal mouse," she says. The mice also had brain changes similar to those seen in people experiencing a migraine.
The findings should help explain the elusive link between sleep patterns and migraine, Charles says. "Disruptions of sleep are very well known to be a migraine trigger," he says. "And many migraine patients will tell you that their migraine attack will only end if they're able to get to sleep."
The results also serve as a reminder that there is a lot more to a migraine than headache and pain, Charles says. He says the study represents "another step toward bringing migraine forward as a disorder of the brain and a disorder for which there's a genetic basis."
But the ultimate payoff of the new research should be new ways to treat or prevent migraines, says Bates, who is now on the faculty at Brigham Young University.
"I know so well how frustrating and really demoralizing it can be to get a migraine," she says. "But I think once we understand the mechanism we can design better drugs."
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It seems somewhat counterintuitive, but the public company with the largest stockpile of cash in the world?Apple, sitting on $145 billion?is borrowing billions of dollars in the financial markets today.
Why? While the company owns a lot of cash, a significant chunk of it is kept overseas, making it tough to bring back. (If Apple does, it?ll have to pay a lot of taxes on it.) And Apple will need a lot of cash over the next couple years because it?s promised to fork over roughly $100 billion?let?s just say that again?$100 billion!?to its shareholders through dividends and stock buybacks.
Of course, Apple isn?t exactly going hat in hand to beg for money. Investors are reportedly throwing dollars at the firm. The bankers managing the deal say the phones are constantly jingling with people looking to fork over their money for iBonds. Of course, the investment bankers?essentially salesman?managing any bond deal almost always say that, but in this case, it seems to be true.
Reuters reports that there?s $50 billion in orders from investors who want to get in on the investment. And while we won?t know exactly how much Apple is going to borrow until the deal prices?that?s when Apple gets its cash?the Journal says it?ll be more than $10 billion. And Reuters suggests?the deal may be the biggest dollar-denominated bond offering ever recorded. A little birdie confirmed that to Bloomberg too, saying the deal will come in around $17 billion. (For the record, that is currently Swiss Pharma giant Roche?s $16.5 billion bond offering in February 2009, according to data provider Dealogic.)
And what will investors get for the billions of cash they?ll be handing over to Apple? Almost nothing. The range of interest rates Apple will reportedly be paying is very very low. Bloomberg reports:
The fixed-rate, three-year debt may pay 25 basis points more than similar-maturity Treasuries; the five-year notes may have a relative yield of 45 basis points; the 10-year securities may have a spread of 80 basis points and the 30-year bonds may pay 105, said the person, who asked not to be identified because terms aren?t set.
So to spell it out a bit more, the US five-year note is currently yielding about 0.67%. Apple expects to be able to borrow for five years at around 1.12%. That?s not only much less than the dodgier European countries like Italy (2.63%) and Spain (2.91%), it?s also lower than respectable sovereigns like Sweden (1.20%) ?and Australia (2.62%). That effectively suggests that Apple would be considered one of the safest places to stash your money on the planet, although not quite as safe as the safest government bond markets such as the US and Germany.
Source: http://qz.com/79790/joining-the-rest-of-america-apple-goes-billions-of-dollars-into-debt/
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